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HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression
Cancer cells develop resistance to therapy by adapting to hypoxic microenvironments, and hypoxia-inducible factors (HIFs) play crucial roles in this process. We investigated the roles of HIF-1α and HIF-2α in cancer cell death induced by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522113/ https://ncbi.nlm.nih.gov/pubmed/28476028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17157 |
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