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NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma

CONTEXT: Anaplastic thyroid carcinoma (ATC) represents one of the most aggressive carcinomas with no consistent survival benefit when treated with conventional radiochemotherapy. Approaches targeting “oncogene addiction” of ATC are increasingly explored and first promising results have been reported...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tiedje, Vera, Ting, Saskia, Herold, Thomas, Synoracki, Sarah, Latteyer, Soeren, Moeller, Lars C., Zwanziger, Denise, Stuschke, Martin, Fuehrer, Dagmar, Schmid, Kurt Werner
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522092/
https://ncbi.nlm.nih.gov/pubmed/28489587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17300
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