Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma

Cancer-associated fibroblasts (CAFs) are believed to influence tumor behavior and clinical outcomes. We previously showed that conditioned medium (CM) from CAFs induces proliferation and motility of esophageal squamous cell carcinoma (ESCC) cells. Here, we investigated the molecular mechanisms by wh...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tian, Baoqing, Chen, Xiaojia, Zhang, Huihua, Li, Xiaoyan, Wang, Jiakang, Han, Wei, Zhang, Li-Yi, Fu, Li, Li, Yan, Nie, Changjun, Zhao, Ying, Tan, Xuan, Wang, Hailong, Guan, Xin-Yuan, Hong, An
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522068/
https://ncbi.nlm.nih.gov/pubmed/28404945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15857
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