Malignant ascites-derived exosomes promote proliferation and induce carcinoma-associated fibroblasts transition in peritoneal mesothelial cells

Malignant ascites-derived exosomes have been demonstrated to participate in tumor metastasis. In peritoneal metastasis, normal mesothelial cells (MCs) can be converted into carcinoma-associated fibroblasts (CAFs) by mesothelial-mesenchymal transition (MMT). Herein, we evaluated the effect of maligna...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Wei, Mingtian, Yang, Tinghan, Chen, Xiangzheng, Wu, Yangping, Deng, Xiangbing, He, Wanbin, Yang, Jinliang, Wang, Ziqiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522065/
https://ncbi.nlm.nih.gov/pubmed/28178689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15040
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