Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

Gliomas are the most common form of malignant primary brain tumors with poor 5-year survival rate. Dysregulation of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) was observed in gliomas, but the specific role and molecular mechanism of PLOD2 in glioma have not been reported yet. In this...

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Vydáno v:Oncotarget
Hlavní autoři: Song, Ye, Zheng, Shihao, Wang, Jizhou, Long, Hao, Fang, Luxiong, Wang, Gang, Li, Zhiyong, Que, Tianshi, Liu, Yi, Li, Yilei, Zhang, Xi’an, Fang, Weiyi, Qi, Songtao
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522040/
https://ncbi.nlm.nih.gov/pubmed/28410212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16710
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