Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

Blockade of the inhibitory PD-1/PD-L1 immune checkpoint axis is a promising cancer treatment. Nonetheless, a significant number of patients and malignancies do not respond to this therapy. To develop a screen for response to PD-1/PD-L1 inhibition, it is critical to develop a non-invasive tool to acc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Broos, Katrijn, Keyaerts, Marleen, Lecocq, Quentin, Renmans, Dries, Nguyen, Tham, Escors, David, Liston, Adrian, Raes, Geert, Breckpot, Karine, Devoogdt, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522039/
https://ncbi.nlm.nih.gov/pubmed/28410210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16708
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