Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach

Hepatocellular carcinoma (HCC) results from accumulation of both genetic and epigenetic alterations. We investigated the genome-wide DNA methylation profile in 69 pairs of HCC and adjacent non-cancerous liver tissues using the Infinium HumanMethylation 450K BeadChip array. An innovative analytical a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gentilini, Davide, Scala, Stefania, Gaudenzi, Germano, Garagnani, Paolo, Capri, Miriam, Cescon, Matteo, Grazi, Gian Luca, Bacalini, Maria Giulia, Pisoni, Serena, Dicitore, Alessandra, Circelli, Luisa, Santagata, Sara, Izzo, Francesco, Di Blasio, Anna Maria, Persani, Luca, Franceschi, Claudio, Vitale, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522036/
https://ncbi.nlm.nih.gov/pubmed/28514750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17462
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