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Processing closely spaced lesions during Nucleotide Excision Repair triggers mutagenesis in E. coli

It is generally assumed that most point mutations are fixed when damage containing template DNA undergoes replication, either right at the fork or behind the fork during gap filling. Here we provide genetic evidence for a pathway, dependent on Nucleotide Excision Repair, that induces mutations when...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Janel-Bintz, Régine, Napolitano, Rita L., Isogawa, Asako, Fujii, Shingo, Fuchs, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521853/
https://ncbi.nlm.nih.gov/pubmed/28686598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006881
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