Partial agonist/antagonist mouse interleukin-2 proteins indicate that a third component of the receptor complex functions in signal transduction.

Some mouse interleukin-2 (mIL-2) proteins with substitutions at residue Gln141 are unable to trigger a maximal biological response. The Asp141 protein induces the lowest maximal response. The Asp141 protein can weakly antagonize the biological activity of mIL-2 and strongly antagonizes the biologica...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zurawski, S M, Imler, J L, Zurawski, G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1990
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC552160/
https://ncbi.nlm.nih.gov/pubmed/2249656
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