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The ligand binding site and transduction mechanism in the inositol-1,4,5-triphosphate receptor.

The inositol-1,4,5-triphosphate (InsP3) receptor consists of a homotetramer of highly conserved 313 kd subunits that contain multiple transmembrane regions in the C-terminal part of the protein. The receptor was expressed in COS cells and its domain structure was studied by mutagenesis. Deletion of...

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Détails bibliographiques
Auteurs principaux: Mignery, G A, Südhof, T C
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC552159/
https://ncbi.nlm.nih.gov/pubmed/2174351
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