Control of replication of plasmid R1: formation of an initial transient complex is rate-limiting for antisense RNA--target RNA pairing.

The replication frequency of plasmid R1 is determined by the availability of the initiator protein RepA. Synthesis of RepA is negatively controlled by an antisense RNA, CopA, which forms a duplex with the upstream region of the RepA mRNA, CopT. We have previously shown that the in vitro formation of...

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Veröffentlicht in:EMBO J
Hauptverfasser: Persson, C, Wagner, E G, Nordström, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1698622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07591.x
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