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Transcriptional and post-transcriptional regulation of tyrosine hydroxylase gene by protein kinase C.

The role played by protein kinase C (PKC) in TH gene regulation was investigated at transcriptional and post-transcriptional levels using PC12 cells. The cells were treated with the phorbol ester TPA, which not only activates PKC but also causes down-regulation. PKC levels were monitored by [3H]PDBU...

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Autores principales: Vyas, S, Faucon Biguet, N, Mallet, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC552126/
https://ncbi.nlm.nih.gov/pubmed/1976513
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