Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

The cDNA for TTF-1, a thyroid nuclear factor that binds to the promoter of thyroid specific genes, has been cloned. The protein encoded by the cDNA shows binding properties indistinguishable from those of TTF-1 present in nuclear extracts of differentiated rat thyroid cells. The DNA binding domain o...

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Bibliographic Details

Published in:	EMBO J
Main Authors:	Guazzi, S, Price, M, De Felice, M, Damante, G, Mattei, M G, Di Lauro, R
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1990
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552115/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1976511/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07574.x
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