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A deep convolutional neural network approach to single-particle recognition in cryo-electron microscopy

BACKGROUND: Single-particle cryo-electron microscopy (cryo-EM) has become a mainstream tool for the structural determination of biological macromolecular complexes. However, high-resolution cryo-EM reconstruction often requires hundreds of thousands of single-particle images. Particle extraction fro...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Zhu, Yanan, Ouyang, Qi, Mao, Youdong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521087/
https://ncbi.nlm.nih.gov/pubmed/28732461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1757-y
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