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Titanium particle-induced osteogenic inhibition and bone destruction are mediated by the GSK-3β/β-catenin signal pathway

Wear debris-induced osteogenic inhibition and bone destruction are critical in the initiation of peri-prosthetic osteolysis. However, the molecular mechanism underlying this phenomenon is poorly understood. In this study, we analyzed the involvement of the GSK-3β/β-catenin signal pathway, which is i...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gu, Ye, Wang, Zhirong, Shi, Jiawei, Wang, Liangliang, Hou, Zhenyang, Guo, Xiaobin, Tao, Yunxia, Wu, Xiexing, Zhou, Wei, Liu, Yu, Zhang, Wen, Xu, Yaozeng, Yang, Huilin, Xue, Feng, Geng, Dechun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520930/
https://ncbi.nlm.nih.gov/pubmed/28617442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.275
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