In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects

In vitro cultured autologous mesenchymal stem cells (MSCs) within passage 5 have been approved for clinical application in stem cell-based treatment of cartilage defects. However, their chondrogenic potential has not yet been questioned or verified. In this study, the chondrogenic potential of bone...

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Publicat a:Cell Death Dis
Autors principals: Jiang, Tongmeng, Xu, Guojie, Wang, Qiuyan, Yang, Lihui, Zheng, Li, Zhao, Jinmin, Zhang, Xingdong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520885/
https://ncbi.nlm.nih.gov/pubmed/28569773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.215
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