Ethanol Withdrawal Drives Anxiety-Related Behaviors by Reducing M-type Potassium Channel Activity in the Lateral Habenula

Alcohol use disorders (AUDs) and anxiety disorders (ADs) are often seen concurrently, but their underlying cellular basis is unclear. For unclear reasons, the lateral habenula (LHb), a key brain region involved in the pathophysiology of ADs, becomes hyperactive after ethanol withdrawal. M-type K(+)...

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Pubblicato in:Neuropsychopharmacology
Autori principali: Kang, Seungwoo, Li, Jing, Zuo, Wanhong, Fu, Rao, Gregor, Danielle, Krnjevic, Kresimir, Bekker, Alex, Ye, Jiang-Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520788/
https://ncbi.nlm.nih.gov/pubmed/28387223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.68
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