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The role of extracellular histone in organ injury

Histones are intra-nuclear cationic proteins that are present in all eukaryotic cells and are highly conserved across species. Within the nucleus, they provide structural stability to chromatin and regulate gene expression. Histone may be released into the extracellular space in three forms: freely,...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Silk, Eleanor, Zhao, Hailin, Weng, Hao, Ma, Daqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520745/
https://ncbi.nlm.nih.gov/pubmed/28542146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.52
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