CAF-secreted CXCL1 conferred radioresistance by regulating DNA damage response in a ROS-dependent manner in esophageal squamous cell carcinoma

Five-year survival rate of esophageal squamous cell carcinoma (ESCC) patients treated with radiotherapy is <20%. Our study aimed to investigate whether cancer-associated fibroblasts (CAFs), one major component of tumor microenvironment, were involved in tumor radioresistance in ESCC. By use of hu...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Hongfang, Yue, Jing, Jiang, Zhenzhen, Zhou, Rongjing, Xie, Ruifei, Xu, Yiping, Wu, Shixiu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520705/
https://ncbi.nlm.nih.gov/pubmed/28518141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.180
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