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Hepatocyte polyploidization and its association with pathophysiological processes

A characteristic cellular feature of the mammalian liver is the progressive polyploidization of the hepatocytes, where individual cells acquire more than two sets of chromosomes. Polyploidization results from cytokinesis failure that takes place progressively during the course of postnatal developme...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Wang, Min-Jun, Chen, Fei, Lau, Joseph T Y, Hu, Yi-Ping
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520697/
https://ncbi.nlm.nih.gov/pubmed/28518148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.167
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