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Structural analogues of schweinfurthin F: Probing the steric, electronic and hydrophobic properties of the D-ring substructure

The natural tetracyclic schweinfurthins are potent and selective inhibitors of cell growth in the National Cancer Institute’s 60-cell line screen. An interest in determination of their cellular or molecular target has inspired our efforts to prepare both the natural products and analogues. In this p...

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Détails bibliographiques
Publié dans:Bioorg Med Chem
Auteurs principaux: Ulrich, Natalie C., Kodet, John G., Mente, Nolan R., Kuder, Craig H., Beutler, John A., Hohl, Raymond J., Wiemer, David F.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520629/
https://ncbi.nlm.nih.gov/pubmed/20116262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.12.063
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