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The pleiotropic regulation of cyclin D1 by newly identified sesaminol-binding protein ANT2

The expression of cyclin D1 is upregulated in various cancer cells by diverse mechanisms, such as increases in mRNA levels, the promotion of the translation by mammalian target of rapamycin complex 1 (mTORC1) signaling and the protein stabilization. We here show that sesaminol, a sesame lignan, redu...

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Détails bibliographiques
Publié dans:Oncogenesis
Auteurs principaux: Watanabe, M, Iizumi, Y, Sukeno, M, Iizuka-Ohashi, M, Sowa, Y, Sakai, T
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520487/
https://ncbi.nlm.nih.gov/pubmed/28368390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.10
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