Mutations of MAP2K1 are frequent in pediatric-type follicular lymphoma and result in ERK pathway activation

Pediatric-type follicular lymphoma (PTFL) is a B-cell lymphoma with distinctive clinicopathological features. Recently, recurrent genetic alterations of potential importance for its pathogenesis that disrupt pathways associated with the germinal center reaction (TNFRSF14, IRF8), immune escape (TNFRS...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Schmidt, Janine, Ramis-Zaldivar, Joan Enric, Nadeu, Ferran, Gonzalez-Farre, Blanca, Navarro, Alba, Egan, Caoimhe, Montes-Mojarro, Ivonne Aidee, Marafioti, Teresa, Cabeçadas, Jose, van der Walt, Jon, Dojcinov, Stefan, Rosenwald, Andreas, Ott, German, Bonzheim, Irina, Fend, Falko, Campo, Elias, Jaffe, Elaine S., Salaverria, Itziar, Quintanilla-Martinez, Leticia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520474/
https://ncbi.nlm.nih.gov/pubmed/28533310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-776278
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