Physiological Concentrations of Amyloid Beta Regulate Recycling of Synaptic Vesicles via Alpha7 Acetylcholine Receptor and CDK5/Calcineurin Signaling

Despite the central role of amyloid β (Aβ) peptide in the etiopathogenesis of Alzheimer’s disease (AD), its physiological function in healthy brain is still debated. It is well established that elevated levels of Aβ induce synaptic depression and dismantling, connected with neurotoxicity and neurona...

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Bibliografiska uppgifter
I publikationen:Front Mol Neurosci
Huvudupphovsmän: Lazarevic, Vesna, Fieńko, Sandra, Andres-Alonso, Maria, Anni, Daniela, Ivanova, Daniela, Montenegro-Venegas, Carolina, Gundelfinger, Eckart D., Cousin, Michael A., Fejtova, Anna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520466/
https://ncbi.nlm.nih.gov/pubmed/28785201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00221
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