Neutrophil Elastase and Interleukin 17 Expressed in the Pig Colon during Brachyspira hyodysenteriae Infection Synergistically with the Pathogen Induce Increased Mucus Transport Speed and Production via Mitogen-Activated Protein Kinase 3

Brachyspira hyodysenteriae colonizes the pig colon, resulting in mucoid hemorrhagic diarrhea and mucus layer changes. These changes are characterized by a disorganized mucus structure and massive mucus induction with de novo expression of MUC5AC and increased production of MUC2. To investigate the m...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Quintana-Hayashi, Macarena P., Navabi, Nazanin, Mahu, Maxime, Venkatakrishnan, Vignesh, Fernandez, Harvey R., Haesebrouck, Freddy, Pasmans, Frank, Lindén, Sara K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520435/
https://ncbi.nlm.nih.gov/pubmed/28559407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00262-17
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