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Myeloid-derived suppressor cells promote B-cell production of IgA in a TNFR2-dependent manner

Myeloid-derived suppressor cells (MDSCs) are well known for their capacity to suppress antitumor T-cell responses, but their effects on B-cell function and antibody production remain unclear. Here, we found that MDSCs that accumulated around the germinal center in the spleen of tumor-bearing mice co...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Xu, Xia, Meng, Qinghong, Erben, Ulrike, Wang, Peigang, Glauben, Rainer, Kühl, Anja A, Wu, Hao, Ma, Chung Wah, Hu, Minghua, Wang, Yuanyuan, Sun, Wei, Jia, Junying, Wu, Xinyi, Chen, Wei, Siegmund, Britta, Qin, Zhihai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520412/
https://ncbi.nlm.nih.gov/pubmed/27133471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.103
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