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Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

The 1:1 complex of the mutant Antp(C39----S) homeodomain with a 14 bp DNA fragment corresponding to the BS2 binding site was studied by nuclear magnetic resonance (NMR) spectroscopy in aqueous solution. The complex has a molecular weight of 17,800 and its lifetime is long compared with the NMR chemi...

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Main Authors: Otting, G, Qian, Y Q, Billeter, M, Müller, M, Affolter, M, Gehring, W J, Wüthrich, K
格式: Artigo
語言:Inglês
出版: 1990
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC552035/
https://ncbi.nlm.nih.gov/pubmed/1976507
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