Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA

BACKGROUND: RBM10 is an RNA binding protein involved in message stabilization and alternative splicing regulation. The objective of the research described herein was to identify novel targets of RBM10-regulated splicing. To accomplish this, we downregulated RBM10 in human cell lines, using small int...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Sutherland, Leslie C., Thibault, Philippe, Durand, Mathieu, Lapointe, Elvy, Knee, Jose M., Beauvais, Ariane, Kalatskaya, Irina, Hunt, Sarah C., Loiselle, Julie J., Roy, Justin G., Tessier, Sarah J., Ybazeta, Gustavo, Stein, Lincoln, Kothary, Rashmi, Klinck, Roscoe, Chabot, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520337/
https://ncbi.nlm.nih.gov/pubmed/28728573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-017-0096-x
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