A phase Ib study of pembrolizumab plus chemotherapy in patients with advanced cancer (PembroPlus)

BACKGROUND: Pembrolizumab (P) is an anti-PD-1 antibody that blocks the interaction between programmed cell death protein 1 (PD-1) on T-cells and PD-L1 and PD-L2 on tumour cells. A phase Ib trial of P plus chemotherapy was undertaken to evaluate the safety and efficacy. METHODS: Patients with advance...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Weiss, Glen J, Waypa, Jordan, Blaydorn, Lisa, Coats, Jessica, McGahey, Kayla, Sangal, Ashish, Niu, Jiaxin, Lynch, Cynthia A, Farley, John H, Khemka, Vivek
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520208/
https://ncbi.nlm.nih.gov/pubmed/28588322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.145
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