Second-line pazopanib in patients with relapsed and refractory small-cell lung cancer: a multicentre phase II study of the Hellenic Oncology Research Group

BACKGROUND: Pazopanib is a tyrosine kinase inhibitor with antiangiogenic activity. Vascular endothelial growth factor expression is increased in SCLC and is correlated with poor prognosis. The efficacy and tolerance of second-line pazopanib in SCLC was evaluated. PATIENTS AND METHODS: Patients with...

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Udgivet i:Br J Cancer
Main Authors: Koinis, F, Agelaki, S, Karavassilis, V, Kentepozidis, N, Samantas, E, Peroukidis, S, Katsaounis, P, Hartabilas, E, Varthalitis, I I, Messaritakis, I, Fountzilas, G, Georgoulias, V, Kotsakis, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520202/
https://ncbi.nlm.nih.gov/pubmed/28510571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.137
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