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Claudin 4-targeted nanographene phototherapy using a Clostridium perfringens enterotoxin peptide-photosensitizer conjugate

In this study we designed a claudin 4-directed dual photodynamic and photothermal system, in which a 30-amino acid claudin 4-binding peptide, Clostridium perfringens enterotoxin (CPE), was linked to a photodynamic agent chlorin e6 (Ce6) through a polyethylene glycol spacer (CPC) and anchored onto re...

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Bibliografiske detaljer
Udgivet i:Acta Pharmacol Sin
Main Authors: Shim, Gayong, Kim, Mi-Gyeong, Jin, Hyerim, Kim, Jinyoung, Oh, Yu-Kyoung
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520197/
https://ncbi.nlm.nih.gov/pubmed/28552914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.46
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