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Central insulin modulates food valuation via mesolimbic pathways

Central insulin is thought to act at the neural interface between metabolic and hedonic drives to eat. Here, using pharmacological fMRI, we show that intranasal insulin (INI) changes the value of food cues through modulation of mesolimbic pathways. Overnight fasted participants rated the palatabilit...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tiedemann, Lena J., Schmid, Sebastian M., Hettel, Judith, Giesen, Katrin, Francke, Paul, Büchel, Christian, Brassen, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520049/
https://ncbi.nlm.nih.gov/pubmed/28719580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16052
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