Effects of presynaptic muscarinic cholinoreceptor blockade on neuromuscular transmission as assessed by the train‐of‐four and the tetanic fade response to rocuronium

This study investigated the effect of muscarinic M(1) and M(2) receptor antagonists on the rocuronium‐induced train of four (TOF) fade and tetanic fade, respectively. Ex‐vivo phrenic nerves and diaphragms were obtained from adult Sprague‐Dawley rats and stabilized in Krebs buffer; the nerve‐stimulat...

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Bibliographic Details
Published in:Clin Exp Pharmacol Physiol
Main Authors: Kim, Yong Beom, Lee, Sangseok, Lee, Kyeong Chun, Kim, Ha Jung, Ro, Young Jin, Yang, Hong‐Seuk
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519946/
https://ncbi.nlm.nih.gov/pubmed/28394450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12763
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