Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis

OBJECTIVE: Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in peripheral blood. Various diseases causing neuronal damage have resulted in elevated CSF concentrations. We explored the value of an ultras...

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Pubblicato in:Ann Neurol
Autori principali: Disanto, Giulio, Barro, Christian, Benkert, Pascal, Naegelin, Yvonne, Schädelin, Sabine, Giardiello, Antonella, Zecca, Chiara, Blennow, Kaj, Zetterberg, Henrik, Leppert, David, Kappos, Ludwig, Gobbi, Claudio, Kuhle, Jens, Lorscheider, Johannes, Yaldizli, Özgür, Derfuss, Tobias, Achtnichts, Lutz, Nedeltchev, Krassen, Kamm, Christian P, Salmen, Anke, Chan, Andrew, Lalive, Patrice H, Pot, Caroline, Schluep, Myriam, Granziera, Cristina, Du Pasquier, Renaud, Müller, Stefanie, Vehoff, Jochen
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519945/
https://ncbi.nlm.nih.gov/pubmed/28512753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24954
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