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Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants
Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of S...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519743/ https://ncbi.nlm.nih.gov/pubmed/28729690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06401-x |
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