Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization

HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Studies have shown that the association of Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef. Using purified recombinant proteins in pull-down as...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Boeske, Alexandra, Schwarten, Melanie, Ma, Peixiang, Tusche, Markus, Mötter, Jessica, Möller, Christina, Neudecker, Philipp, Hoffmann, Silke, Willbold, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519724/
https://ncbi.nlm.nih.gov/pubmed/28729737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06319-4
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