Nucleocytoplasmic Shuttling of Histone Deacetylase 9 Controls Activity-Dependent Thalamocortical Axon Branching

During development, thalamocortical (TC) axons form branches in an activity-dependent fashion. Here we investigated how neuronal activity is converted to molecular signals, focusing on an epigenetic mechanism involving histone deacetylases (HDACs). Immunohistochemistry demonstrated that HDAC9 was tr...

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Published in:Sci Rep
Main Authors: Alchini, Ricardo, Sato, Haruka, Matsumoto, Naoyuki, Shimogori, Tomomi, Sugo, Noriyuki, Yamamoto, Nobuhiko
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519695/
https://ncbi.nlm.nih.gov/pubmed/28729685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06243-7
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