Lowered fasting chenodeoxycholic acid correlated with the decrease of fibroblast growth factor 19 in Chinese subjects with impaired fasting glucose

The gut-derived hormone Fibroblast growth factor 19 (FGF19) could regulate glucose metabolism and is induced by bile acids (BAs) through activating Farnesoid X Receptor (FXR). FGF19 was found to decrease in subjects with isolated-impaired fasting glucose (I-IFG) and type 2 diabetes mellitus (T2DM)....

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Publicado no:Sci Rep
Main Authors: Zhang, Jing, Li, Huating, Zhou, Hu, Fang, Li, Xu, Jingjing, Yan, Han, Chen, Shuqin, Song, Qianqian, Zhang, Yinan, Xu, Aimin, Fang, Qichen, Ye, Yang, Jia, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519593/
https://ncbi.nlm.nih.gov/pubmed/28729691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06252-6
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