AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists

While peptide antagonists for the gastrin-releasing peptide receptor (BB(2)R), neuromedin B receptor (BB(1)R), and bombesin (BB) receptor subtype-3 (BRS-3) exist, there is a need to develop non-peptide small molecule inhibitors for all three BBR. The BB agonist (BA)1 binds with high affinity to the...

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Foilsithe in:Front Endocrinol (Lausanne)
Main Authors: Moody, Terry W., Tashakkori, Nicole, Mantey, Samuel A., Moreno, Paola, Ramos-Alvarez, Irene, Leopoldo, Marcello, Jensen, Robert T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Endocrinology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519534/
https://ncbi.nlm.nih.gov/pubmed/28785244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00176
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