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A (64)Cu-labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor
PURPOSE: Determine the efficacy of a 45-amino acid Gp2 domain, engineered to bind to epidermal growth factor receptor (EGFR), as a positron emission tomography (PET) probe of EGFR in a xenograft mouse model. METHODS: The EGFR-targeted Gp2 (Gp2-EGFR) and a non-binding control were site-specifically l...
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Publicado en: | Mol Pharm |
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Autores principales: | , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519506/ https://ncbi.nlm.nih.gov/pubmed/27696863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00538 |
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