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CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic

CTCF is a haploinsufficient tumour suppressor gene with diverse normal functions in genome structure and gene regulation. However the mechanism by which CTCF haploinsufficiency contributes to cancer development is not well understood. CTCF is frequently mutated in endometrial cancer. Here we show th...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Marshall, A D, Bailey, C G, Champ, K, Vellozzi, M, O'Young, P, Metierre, C, Feng, Y, Thoeng, A, Richards, A M, Schmitz, U, Biro, M, Jayasinghe, R, Ding, L, Anderson, L, Mardis, E R, Rasko, J E J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519450/
https://ncbi.nlm.nih.gov/pubmed/28319062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.25
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