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Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging

Fluorogenic probes are invaluable tools for spatiotemporal investigations within live cells. In common fluorogenic probes, the intrinsic fluorescence of a small-molecule fluorophore is masked by esterification until entry into a cell, where endogenous esterases catalyze the hydrolysis of the masking...

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Foilsithe in:J Org Chem
Main Authors: Chyan, Wen, Kilgore, Henry R., Gold, Brian, Raines, Ronald T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519408/
https://ncbi.nlm.nih.gov/pubmed/28345343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b00285
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