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Sequential steps of CRAC channel activation

Interaction between the endoplasmic-reticulum protein STIM1 and the plasma-membrane channel Orai1 generates calcium signals that are central for diverse cellular functions. How STIM1 binds and activates Orai1 remains poorly understood. Using electrophysiological, optical and biochemical techniques,...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Palty, Raz, Fu, Zhu, Isacoff, Ehud Y
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519287/
https://ncbi.nlm.nih.gov/pubmed/28564609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.025
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