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Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment

Diallyl trisulfide (DATS), a garlic organosulfide, has shown excellent chemopreventive potential. Cisplatin (DDP) is widely used to treat solid malignant tumors, but causing serious side effects. In the current study, we attempted to elucidate the chemopreventive mechanisms of DATS in human gastric...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Principais autores: Jiang, Xiao-yan, Zhu, Xiao-song, Xu, Hong-ya, Zhao, Zhong-xi, Li, Si-ying, Li, Shan-zhong, Cai, Jian-hua, Cao, Ji-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519247/
https://ncbi.nlm.nih.gov/pubmed/28344324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.176
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