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Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation

Although the pathogenesis of non-alcoholic fatty liver disease (NAFLD) is not completely understood, the increased influx of free fatty acids (FFAs) into the liver and the FFA-induced hepatic endoplasmic reticulum (ER) stress are two crucial pathogenic processes in the initiation and development of...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Zhou, Bing, Zhou, Dan-li, Wei, Xiao-hong, Zhong, Rong-yu, Xu, Jie, Sun, Liao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519246/
https://ncbi.nlm.nih.gov/pubmed/28344322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.175
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