Atorvastatin reduces β-Adrenergic dysfunction in rats with diabetic cardiomyopathy

BACKGROUND: In the diabetic heart the β-adrenergic response is altered partly by down-regulation of the β1-adrenoceptor, reducing its positive inotropic effect and up-regulation of the β3-adrenoceptor, increasing its negative inotropic effect. Statins have clinical benefits on morbidity and mortalit...

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Foilsithe in:PLoS One
Main Authors: Carillion, Aude, Feldman, Sarah, Na, Na, Biais, Matthieu, Carpentier, Wassila, Birenbaum, Aurélie, Cagnard, Nicolas, Loyer, Xavier, Bonnefont-Rousselot, Dominique, Hatem, Stéphane, Riou, Bruno, Amour, Julien
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519044/
https://ncbi.nlm.nih.gov/pubmed/28727746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180103
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