Protein tyrosine phosphatase 1B is a mediator of cyclic ADP ribose-induced Ca(2+) signaling in ventricular myocytes

Cyclic ADP-ribose (cADPR) releases Ca(2+) from ryanodine receptor (RyR)-sensitive calcium pools in various cell types. In cardiac myocytes, the physiological levels of cADPR transiently increase the amplitude and frequency of Ca(2+) (that is, a rapid increase and decrease of calcium within one secon...

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Pubblicato in:Exp Mol Med
Autori principali: Park, Seon-Ah, Hong, Bing-Zhe, Ha, Ki-Chan, Kim, Uh-Hyun, Han, Myung-Kwan, Kwak, Yong-Geun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519013/
https://ncbi.nlm.nih.gov/pubmed/28572573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.68
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