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Transcription of a nematode trans-spliced leader RNA requires internal elements for both initiation and 3' end-formation.

We have used block substitution mutagenesis and in vitro transcription to define sequence elements important for efficient initiation and 3' end-formation of the trans-spliced leader RNA (SL RNA) of the parasitic nematode Ascaris lumbricoides. These experiments indicate that the SL RNA has an unusua...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Hannon, G J, Maroney, P A, Ayers, D G, Shambaugh, J D, Nilsen, T W
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551899/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2347310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb08318.x
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