The tetravalent formulation of domain III-capsid proteins recalls memory B- and T-cell responses induced in monkeys by an experimental dengue virus infection

Tetra DIIIC is a vaccine candidate against dengue virus (DENV) composed by four chimeric proteins that fuse the domain III of the envelope protein of each virus to the corresponding capsid protein. Containing B- and T-cell epitopes, these proteins form aggregates after the incubation with an immunos...

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Publicado en:Clin Transl Immunology
Autores principales: Gil, Lázaro, Lazo, Laura, Valdés, Iris, Suzarte, Edith, Yen, Phuong, Ramírez, Rosa, Álvarez, Mayling, Dung, Le T, Cobas, Karem, Marcos, Ernesto, Pérez, Yusleidi, Guzmán, María G, D Hien, Ngyen, Guillén, Gerardo, Hermida, Lisset
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518957/
https://ncbi.nlm.nih.gov/pubmed/28748091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2017.24
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