Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models

OBJECTIVES: Cathepsin L (CTSL) and B (CTSB) have a crucial role in extracellular matrix (ECM) degradation and tissue remodeling, which is a prominent feature of fibrogenesis. The aim of this study was to determine the role and clinical significance of these cathepsins in liver fibrosis. METHODS: Hep...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Manchanda, Mansi, Das, Prasenjit, Gahlot, Gaurav P S, Singh, Ratnakar, Roeb, Elke, Roderfeld, Martin, Datta Gupta, Siddhartha, Saraya, Anoop, Pandey, R M, Chauhan, Shyam S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518948/
https://ncbi.nlm.nih.gov/pubmed/28617446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2017.25
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